Click the Evaluate button.
Put the fitness of the genotypes (relative or numbers) and
you can run one generation at the time by pressing the button +1 generation!,
or you can get a graph over gene frequency changes over 60 generations by pressing
the Run button. The corresponding data you can extract over the clip board in the
lower left window.
If you define population size (pop. size) you can simulate random changes in gene frequencies over time.
If you define more populations (number of pop.) you get an average estimate of the gene frequencies over generations and its standard error.
If you use large and many populations the simulation might take several minutes, start with few and small populations so you can have an impression of the time consumption on your computer.
For utilization of a deterministic model go to the program 3.4 and its explanation.
If you have a genetic system (Aa) with gene frequency q=.5. and you have random mating. How many populations out of ten would either have lost or fixed the gene a after 20 generations ? after 40 ? and after 60 generations ?
Put 10 in the pop size box, and pres Run 10 times recording loss or fixation of gene 'a' in each run.
Genotype AA Aa aa Total Observed numbers 225 157 43 Frequency p2 2pq q2 = 1,00 Fitness 1-s1 1 1-s2 Proportion p2(1-s1) 2pq q2(1-s2) = 1-p2s1 - q2s2 after selection
Will equilibrium within 0.02 units be reached ?